ParkinsonFranceV1, Main, Exploration, bibRecord, 000919

Mitophagy mechanisms and role in human diseases

Identifieur interne : 000919 ( Main/Exploration ); précédent : 000918; suivant : 000920

Mitophagy mechanisms and role in human diseases

Auteurs : Matthew Redmann [États-Unis] ; Matthew Dodson [États-Unis] ; Michaël Boyer-Guittaut [France] ; Victor Darley-Usmar [États-Unis] ; Jianhua Zhang [États-Unis]

Source :

The international journal of biochemistry & cell biology [ 1357-2725 ] ; 2014.

RBID : PMC:4111979

English descriptors

KwdEn :
- Heart Diseases (genetics), Heart Diseases (metabolism), Heart Diseases (pathology), Humans, Membrane Potential, Mitochondrial, Mitochondrial Degradation (genetics), Neoplasms (genetics), Neoplasms (metabolism), Neoplasms (pathology), Parkinson Disease (genetics), Parkinson Disease (metabolism), Parkinson Disease (pathology).
MESH :
- genetics : Heart Diseases, Mitochondrial Degradation, Neoplasms, Parkinson Disease.
- metabolism : Heart Diseases, Neoplasms, Parkinson Disease.
- pathology : Heart Diseases, Neoplasms, Parkinson Disease.
- Humans, Membrane Potential, Mitochondrial.

Abstract

Mitophagy is a process of mitochondrial turnover through lysosomal mediated autophagy activities. This review will highlight recent studies that have identified mediators of mitophagy in response to starvation, loss of mitochondrial membrane potential or perturbation of mitochondrial integrity. Furthermore, we will review evidence of mitophagy dysfunction in various human diseases and discuss the potential for therapeutic interventions that target mitophagy processes.

Url:

http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4111979

DOI: 10.1016/j.biocel.2014.05.010
PubMed: 24842106
PubMed Central: 4111979

Affiliations:

Le document en format XML

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<front><div type="abstract" xml:lang="en"><p id="P1">Mitophagy is a process of mitochondrial turnover through lysosomal mediated autophagy activities. This review will highlight recent studies that have identified mediators of mitophagy in response to starvation, loss of mitochondrial membrane potential or perturbation of mitochondrial integrity. Furthermore, we will review evidence of mitophagy dysfunction in various human diseases and discuss the potential for therapeutic interventions that target mitophagy processes.</p>
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La maladie de Parkinson en France (serveur d'exploration)

Mitophagy mechanisms and role in human diseases

Mitophagy mechanisms and role in human diseases

Source :

English descriptors

Abstract

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Le document en format XML

Pour manipuler ce document sous Unix (Dilib)

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	La maladie de Parkinson en France (serveur d'exploration)
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